DUAL-ENERGY COMPUTED TOMOGRAPHY FOR EARLY PREDICTION OF POST-THROMBECTOMY HEMORRHAGE: A PILOT STUDY
DOI:
https://doi.org/10.59354/ydth175.2025.404Keywords:
Dual-energy CT, acute ischemic stroke, intracerebral hemorrhage, endovascular thrombectomyAbstract
Objective: To evaluate the predictive value of qualitative features and quantitative indices derived from parenchymal contrast staining (CS) and from the superior sagittal sinus (SSS) on dual-energy CT (DECT) for post-procedural intracerebral hemorrhage (ICH) after endovascular thrombectomy (EVT) in acute ischemic stroke patients.
Materials and Methods: We conducted a retrospective–prospective study including 30 patients with acute ischemic stroke who underwent EVT and DECT within 24 hours post-procedure at Military Hospital 175 between July 2024 and July 2025. Predictive performance of qualitative CS characteristics and quantitative indices from CS regions and the SSS were analyzed for association with post-EVT ICH.
Results: ICH occurred in 6 of 30 patients (20%). Significant DECT predictors of ICH included mixed CS distribution pattern, the “bright spot” sign on iodine overlay maps, a maximum SSS attenuation at 120 kV <52.7 HU (AUC=0,847; sensitivity 66.7%, specificity 100%), and a relative iodine concentration compared with SSS >218% (AUC=0.978; sensitivity 100%, specificity 89%).
Conclusion: DECT provides high predictive value for post-EVT ICH using both qualitative features and quantitative parameters from CS regions and the SSS.
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