CASE REPORT: SURGICAL RESECTION OF A GIANT MEDIASTINAL TERATOMA AT MILITARY HOSPITAL 175
DOI:
https://doi.org/10.59354/ydth175.2025.412Keywords:
mediastinal teratomaAbstract
Mediastinal teratomas develop silently and can grow large without symptoms. When sufficiently enlarged, they may compress the heart, blood vessels, esophagus, trachea, and lungs, causing chest pain, shortness of breath, and coughing. Computed tomography (CT) is essential for diagnosis and treatment planning. We report a case of giant mediastinal teratoma resection at Military Hospital 175. A 34-year-old female patient was admitted due to persistent right chest pain and dyspnea. CT imaging revealed a large tumor compressing the right lung, heart, and major blood vessels. Bronchoscopy and transthoracic biopsy confirmed the mediastinal teratoma diagnosis. The patient underwent surgical resection, successfully removing the tumor without invasion of adjacent structures. Postoperatively, she recovered well. Histopathological analysis confirmed a mature teratoma. Surgery remains the optimal treatment for mediastinal teratomas, ensuring complete tumor removal and improved patient outcomes.
References
1. Goyal VD, Pahade A, Misra G, Kaira V, Prajapati N. Large mediastinal/ thoracic benign teratoma presenting with haemoptysis: Report of a case and review of the literature. Lung India. 2023 Mar-Apr;40(2):155-60. doi: 10.4103/lungindia. lungindia_198_22.
2. Kang J, Mashaal H, Anjum F. Mediastinal Germ Cell Tumors. StatPearls. 2024.
3. Mardani P, Naseri R, Amirian A, et al. Intrapulmonary mature cystic teratoma of the lung: case report of a rare entity. BMC Surg. 2020 Sep 14;20(1):203. doi: 10.1186/s12893-020-00864-y.
4. Wang R, Li H, Jiang J, Xu GJ. Incidence, treatment, and survival analysis in mediastinal malignant teratoma population. J Thorac Cancer Res. 2020;9(4):2492-502.
5. Cung Văn Công. U quái thành thục lành tính trong trung thất ở bệnh nhi - báo cáo ca bệnh và xem xét tài liệu liên quan. Tạp chí Y học Việt Nam. 2022; 522:53-60.
6. Mustafa OM, Mohammed SF, Aljubran A, Saleh WN. Immature mediastinal teratoma with unusual histopathology: A case report of multi-lineage, somatic-type malignant transformation and a review of the literature. Medicine (Baltimore). 2016 Jun;95(26): e3378. doi: 10.1097/MD.0000000000003378.
7. No TH, Seol SH, Seo GW, et al. Benign mature teratoma in anterior mediastinum. J Clin Med Res. 2015 Sep;7(9):726-8. doi: 10.14740/jocmr2270w.
8. Moraru L, Mitranovici MI, Chiorean DM, et al. Immature teratoma: Diagnosis and management - A review of the literature. Diagnostics (Basel). 2023 Apr 23;13(9). doi: 10.3390/diagnostics13091516.
9. Tian Z, Liu H, Li S, et al. Surgical treatment of benign mediastinal teratoma: Summary of experience of 108 cases. J Cardiothorac Surg. 2020 Feb 17;15(1):36. doi: 10.1186/s13019-020-1075-8.
