LIVER INJURY IN SEVERE AND CRITICAL COVID-19 PATIENTS TREATED AT INFECTIOUS FIELD HOSPITAL NO.5G
DOI:
https://doi.org/10.59354/ydth175.2023.74Keywords:
Liver injury, COVID-19Abstract
Objectives: To evaluate liver injury in severe and critical COVID-19 patients, who were treated in Infectious Field Hospital No.5G.
Patients and methods: A respective cohort study on 156 severe and critical COVID-19 patients in ICU of Infectious Field Hospital No.5G- Hochiminh city from August to November 2021.
Results: 48.7% of patients had a liver injury, almost at a mild level (25%). Mean survivor time in the group without liver injury (17.96 ± 1.57 days) was higher than the group with liver injury ( 11.89 ± 0.89 days), statistical significance with p = 0.0073.
Conclusion: Severe and critical COVID-19 patients who had liver injury were major at a mild level. The more serve of liver injury was, the higher of concentration of AST and total bilirubin were. Mean survivor time of group without liver injury was higher than the group with liver injury.
References
Anastasiou OE, et al. (2021), Mild versus severe liver injury in SARS-CoV-2 infection. Dig Dis; 39 (1):52-57.
Guo-Guang Ma, Y XS, Ling Wu (2020), Effect of liver injury on prognosis and treatment of hospitalized patients with COVID-19 pneumonia. Annals of Translational Medicine; 9 (1):10.
Phipps MM, et al. (2020), Acute liver injury in COVID-19: Prevalence and association with clinical outcomes in a large U.S cohort, Hepatology; 72 (3):807- 817.
Bloom PP, et al. (2021), Liver biochemistries in hospitalized patients with COVID-19, Hepatology; 73 (3):890- 900.
Ma GG, et al. (2021), Effect of liver injury on prognosis and treatment of hospitalized patients with COVID-19 pneumonia, Ann Transl Med; 9 (1):10.
Shen JX, et al. (2021), Risk factors and prognosis in patients with COVID-19 and liver injury: A retrospective analysis, J Multidiscip Health; 14:629- 637.
Lin Fu JF, Shen Xu (2020), Acute liver injury and its association with death risk of patients with COVID-19, medRx iv; 2:22.
Thống kê dân số Thành phố Hồ Chí Minh (2021), Viện nghiên cứu phát triển thành phố Hồ Chí Minh.
Singh, S. and A. Khan (2020), Clinical characteristics and outcomes of coronavirus disease 2019 among patients with preexisting liver disease in the United States: A Multicenter Research Network Study, Gastroenterology; 159(2): p. 768- 771 e3.
Yang, H.Y., B. Jin, and Y.L. Mao (2020), Liver injury in COVID-19: What do we know now, Hepatobiliary Pancreat Dis Int, 19(5): p. 407-408.
